Actively Recruiting
SABER Study for Selected Early Stage Breast Cancer
Led by University of Miami · Updated on 2025-06-08
18
Participants Needed
1
Research Sites
403 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.
CONDITIONS
Official Title
SABER Study for Selected Early Stage Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female, 50 years of age or older
- Oncotype or MammaPrint diagnosis results obtained before treatment
- Histologically confirmed invasive breast cancer
- Clinical stage T1N0M0 breast cancer
- Estrogen-Receptor/Progesterone-Receptor positive and HER2 negative receptor status
- Unifocal breast cancer
- Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
- Ability to undergo MRI
- Women of child-bearing potential must use contraception or abstain and have a negative pregnancy test at enrollment
- Ability to understand the study and provide informed consent
You will not qualify if you...
- No histologically confirmed invasive breast cancer
- No Oncotype or MammaPrint diagnosis results at treatment start
- Metastatic disease present
- Eastern Cooperative Oncology Group (ECOG) performance status 2, 3, or 4
- Unable to undergo MRI
- Prior radiation therapy to the chest
- History of collagenous diseases such as systemic lupus erythematosus, scleroderma, or dermatomyositis
- Serious medical or psychiatric illness interfering with study compliance
- Diagnosis of another primary cancer within the last 5 years except non-melanoma skin cancer
- Unable to consent, pregnant, nursing, or prisoner
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Miami
Miami, Florida, United States, 33136
Actively Recruiting
Research Team
Z
Zuzel Rodriguez
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
1
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