Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05794464

The SAFE Prospective Registry

Led by University Hospital Ostrava · Updated on 2023-09-07

60

Participants Needed

1

Research Sites

169 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Secretoneurin (SN) is a neuropeptide from the chromogranin family that influences intracellular calcium handling. SN suppresses calcium leakage from the sarcoplasmic reticulum through the ryanodine receptor. SN is a novel biomarker that has shown the potential to predict adverse arrhythmic events.

CONDITIONS

Official Title

The SAFE Prospective Registry

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Atrial fibrillation (paroxysmal or persistent)
  • Patients indicated for catheter ablation and/or electrical cardioversion
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Longstanding or permanent atrial fibrillation
  • Severe mitral regurgitation
  • Heart failure with permanently reduced ejection fraction
  • Cerebral ischaemic stroke in less than 3 months
  • Severe kidney injury
  • Severe renal insufficiency
  • Hepatic insufficiency limiting biomarker sampling
  • Myocardial infarction less than 3 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Ostrava

Ostrava, Moravian-Silesian Region, Czechia, 70852

Actively Recruiting

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Research Team

J

Jiří Hynčica

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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