Actively Recruiting

Phase 2
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT02844738

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder

Led by VivaTech International, Inc. · Updated on 2025-10-14

4000

Participants Needed

1

Research Sites

578 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the shoulder. Follow-up will consist of a larger sample including 4,000 patients.

CONDITIONS

Official Title

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with osteoarthritis of the shoulder caused by degeneration or chronic injury
  • Age between 18 and 90 years
  • Ability to follow the treatment plan, laboratory tests, and periodic interviews
  • Adequate kidney function with creatinine ≤ 1.5 mg/dl
  • Adequate heart and lung function
  • Adequate blood clotting activity with PT(INR) < 1.5 and APTT within normal limits
  • Adequate immune system with no known immunodeficiency
  • Shoulder pain on the affected side lasting more than 6 months
Not Eligible

You will not qualify if you...

  • History of cancer within 5 years before screening, except resolved skin basal cell or squamous cell cancer
  • Presence of serious or unstable heart, brain, or stroke-related conditions
  • Transient ischemic attack diagnosed within 6 months before screening
  • Infection with hepatitis B, hepatitis C, or HIV
  • Body Mass Index over 40 kg/m2
  • Active infection at the time of screening
  • Any illness, psychiatric disorder, or substance dependence considered unsuitable by the investigator
  • Treatments that may affect pain or mobility evaluation, including:
    • Strong opioid use for non-shoulder pain within 4 weeks
    • Corticosteroid injection at the shoulder treatment site within 1 month
    • Regular use of NSAIDs within 48 hours of the procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VivaTech International, Inc.

Grove City, Pennsylvania, United States, 16127

Actively Recruiting

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Research Team

S

Scott M Herkes, MBA

CONTACT

M

Michael P Hutchinson, DVM

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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