Actively Recruiting
Safety and Efficacy of Ear Acupuncture for Antituberculosis Drug-Related Nausea and Vomiting
Led by Indonesia University · Updated on 2025-12-09
58
Participants Needed
1
Research Sites
33 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will look at whether press-needle ear acupuncture can help lower nausea and vomiting caused by antituberculosis medicines in people with pulmonary tuberculosis. Nausea and vomiting are common side effects of tuberculosis treatment, and they can make people stop taking their medicines When treatment is stopped too early, tuberculosis may not be cured and may become resistant to medicines. Participants in this study will have nausea and vomiting related to their tuberculosis treatment. They will be randomly assigned to one of two groups. One group will receive press-needle ear acupuncture. The other group will receive a placebo version that looks similar but does not stimulate acupuncture points Researchers will check nausea and vomiting scores before treatment, during treatment, and after treatment to see whether press-needle acupuncture works better than placebo and whether it is safe. Press-needle acupuncture may help reduce nausea and vomiting by affecting nerves and lowering certain chemicals that trigger these symptoms, and it has minimal side effects If this method is proven helpful and safe, it may give patients a comfortable and low-risk way to manage nausea and vomiting during tuberculosis treatment
CONDITIONS
Official Title
Safety and Efficacy of Ear Acupuncture for Antituberculosis Drug-Related Nausea and Vomiting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants are individuals diagnosed with drug-sensitive tuberculosis or drug-resistant tuberculosis receiving short-term treatment regimens (BPaL/BPaLM)
- Participants are aged 17 years or older.
- Participants experience nausea and vomiting after taking antituberculosis drugs.
- Participants are willing to comply with the study schedule until completion and provide written informed consent.
You will not qualify if you...
- Presence of skin lesions at the site where press needles (PN) will be applied
- Participants who experience nausea and vomiting prior to antituberculosis treatment (including comorbidities that may cause nausea and vomiting, such as renal failure and liver disorders)
- Participants with drug-resistant tuberculosis (DR-TB) receiving long-term or individualized treatment regimens
- Participants with diabetes mellitus and a random blood glucose level > 200 mg/dL
- Participants with unstable hemodynamic status
- Participants who have received acupuncture therapy within the last 2 weeks
- Participants with coagulation disorders (platelet count < 50,000/µL)
- Participants with a history of hypersensitivity reactions to previous acupuncture treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
RSUP Persahabatan
Jakarta, Jakarta Timur, Indonesia, 13230
Actively Recruiting
Research Team
K
Kevin Supratman, MD
CONTACT
K
KEPK RSUPP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here