Actively Recruiting
Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans
Led by Minicircle · Updated on 2026-02-17
24
Participants Needed
2
Research Sites
42 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to investigate the safety and efficacy of a gene therapy for Klotho, delivered via a nonviral plasmid in healthy adult volunteers. Additionally, this study seeks to understand the cognitive and health benefits of the Klotho gene therapy.
CONDITIONS
Official Title
Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant is open to morphological change
- If female, participant agrees to maintain contraception
- If female, participant agrees to take a pregnancy test
- If female, participant agrees to a pregnancy waiver
You will not qualify if you...
- Women of childbearing potential who are unwilling or unable to use effective contraception for the duration of the study
- History of cancer diagnosis
- Preexisting medical issues that may be exacerbated by the treatment
- Has received any gene therapy within the past 12 months
- Unwilling or unable to provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Apeiron Center
Austin, Texas, United States, 78701
Actively Recruiting
2
GARM Clinic
Roatán, Bay Islands, Honduras
Not Yet Recruiting
Research Team
M
Mac Davis
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here