Actively Recruiting
Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke
Led by Yi Yang · Updated on 2024-10-02
100
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine the efficacy and safety of levofloxacin in treating acute ischemic stroke.
CONDITIONS
Official Title
Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-75 years
- Clinical diagnosis of acute ischemic stroke with NIHSS score between 5 and 15 and NHISS score 1a level of consciousness less than 1 point
- Modified Rankin Scale score of 1 or less before stroke onset
- Signed and dated informed consent obtained
You will not qualify if you...
- Patients with transient ischemic attack or undergoing emergency reperfusion therapy such as intravenous thrombolysis or emergency thrombectomy
- Use of glucocorticoids, class I or III antiarrhythmic drugs, or quinolones within 14 days
- Presence of diseases increasing risk of adverse drug reactions including ventricular arrhythmias, prolonged QT interval, severe cardiac insufficiency (NYHA grade 3 or higher), myasthenia gravis, peripheral neuropathy, seizures, tendon diseases, severe immune or hematological diseases, active hepatitis or cirrhosis, serious respiratory diseases
- Abnormal liver or kidney function exceeding specified laboratory limits
- Concurrent infection
- Blood glucose lower than 3.9 mmol/L
- Allergy to fluoroquinolones or other antibiotics
- Life expectancy less than 3 months or inability to complete the study
- Unwillingness for follow-up or poor treatment compliance
- Participation in other clinical studies within 3 months or current participation
- Other conditions unsuitable for enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
First Hospital of Jilin University
Changchun, Jilin, China, 130000
Actively Recruiting
Research Team
Y
Yi Yang, PhD
CONTACT
Z
Zhenni Guo, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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