Actively Recruiting
Safety and Efficacy of Oral NXC-736 in Adult Participants With Moderate and Severe Alopecia Areata
Led by NEXTGEN Bioscience · Updated on 2026-04-13
73
Participants Needed
2
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the safety and efficacy of NXC-736 monotherapy in participants with severe alopecia areata (AA).
CONDITIONS
Official Title
Safety and Efficacy of Oral NXC-736 in Adult Participants With Moderate and Severe Alopecia Areata
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men or women between 19 and 65 years of age at the time of informed consent
- Moderate and severe alopecia areata with a SALT score of 25% to less than 95% at Screening and Day 1/Baseline
- Current episode of hair loss lasting 6 months or more but less than 8 years
- Stable disease condition with no significant hair growth in the last 6 months as assessed by the Investigator
- Willing to keep the same hairstyle and hair color for the duration of the study
You will not qualify if you...
- History of alopecia types other than alopecia areata, such as cicatricial/scarring alopecia (including central centrifugal cicatricial alopecia), traction alopecia, androgenic alopecia, or telogen effluvium
- Active scalp inflammation, infection, psoriasis, or other scalp conditions that may interfere with the SALT assessment
- Prior use of Janus kinase (JAK) inhibitors (oral or topical) or participation in clinical studies involving JAK inhibitors
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Seoul National University Hospital.
Seoul, South Korea, 03080
Actively Recruiting
2
Kyung Hee University Hospital at Gangdong
Seoul, South Korea, 05278
Actively Recruiting
Research Team
H
Heesun Kim
CONTACT
Y
YangHye Park
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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