Actively Recruiting
The Safety and Efficacy of PD-1 Monoantrapical Chemotherapy in the Treatment of Local Advanced Stomach Cancer
Led by The First Hospital of Jilin University · Updated on 2021-08-11
30
Participants Needed
1
Research Sites
256 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To explore the safety and efficacy of local advanced stomach cancer patients receiving new complementary treatment of PD-1 monoantiotherapy before surgery
CONDITIONS
Official Title
The Safety and Efficacy of PD-1 Monoantrapical Chemotherapy in the Treatment of Local Advanced Stomach Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed adenocarcinoma of the stomach with PD-L1 positive (CPS =1)
- Clinical stage cT3-4a/N+M0 confirmed by endoscopy, abdominal CT, and laparoscopy
- Tumors can be surgically removed by distal gastrectomy with D2 lymph node dissection aiming for R0 or R1 resection
- No bulky lymph node metastasis detected by abdominal CT
- No pleural effusion, ascites beyond pelvis, or metastasis to peritoneum, liver, or other distant organs
- No clinically apparent distant metastasis
- Karnofsky performance status of 70% or higher
- Able to take oral nutrition sufficiently
- No prior chemotherapy or radiation therapy for any tumors
- No previous surgery for the current stomach cancer
- Adequate organ function confirmed by lab tests at least 7 days after anticancer drugs, including specific blood counts and liver/kidney function limits
- No emergency surgery needed due to tumor bleeding or perforation
- No mechanical obstruction of the stomach
- Provided written informed consent
You will not qualify if you...
- History of upper abdominal surgery
- History of surgery on the gastrointestinal tract
- Body mass index over 30 kg/m2
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
the First Hospital of Jilin University
Changchun, Jilin, China, 130000
Actively Recruiting
Research Team
D
Di Guo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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