Actively Recruiting
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
Led by Pfizer · Updated on 2026-05-12
91
Participants Needed
31
Research Sites
339 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a Phase 2, open-label, multicenter, multiple subcutaneous injection, safety and efficacy study of PF-06835375 in adult participants with primary immune thrombocytopenia (ITP). This study will focus on participants with persistent (\>3 months and ≤12 months), or chronic (\>12 months) ITP
CONDITIONS
Official Title
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Primary ITP with ongoing platelet counts less than 50 x 10^9/L and no severe bleeding within 1 month or during screening
- Persistent ITP lasting more than 3 months and up to 12 months, or chronic ITP lasting more than 12 months
You will not qualify if you...
- Severe bleeding event (WHO grade 2 or higher) within 4 weeks before screening, or current bleeding requiring standard treatment or blood products
- Splenectomy within 3 months before randomization or planned during the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 31 locations
1
East Carolina University
Greenville, North Carolina, United States, 27834
Actively Recruiting
2
Liverpool Hospital
Liverpool, New South Wales, Australia, 2170
Actively Recruiting
3
South West Radiology
Liverpool, New South Wales, Australia, 2170
Actively Recruiting
4
Slade Pharmacy
Mount Kuring-Gai, New South Wales, Australia, 2080
Actively Recruiting
5
Calvary Mater Newcastle
Waratah, New South Wales, Australia, 2298
Actively Recruiting
6
Flinders Medical Centre
Bedford Park, South Australia, Australia, 5042
Actively Recruiting
7
ICON Cancer Centre - Kurralta Park
Kurralta Park, South Australia, Australia, 5037
Actively Recruiting
8
The Alfred Hospital
Melbourne, Victoria, Australia, 3004
Actively Recruiting
9
Royal Perth Hospital
Perth, Western Australia, Australia, 6000
Actively Recruiting
10
Unity Health Toronto, St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8
Actively Recruiting
11
McGill University Health Centre
Montreal, Quebec, Canada, H4A 3J1
Actively Recruiting
12
Fakultni nemocnice Hradec Kralove
Hradec Králové, Czechia, 500 05
Actively Recruiting
13
Fakultni nemocnice Ostrava
Ostrava - Poruba, Czechia, 708 52
Actively Recruiting
14
Fakultni nemocnice Kralovske Vinohrady
Prague, Czechia, 100 34
Actively Recruiting
15
Vseobecna fakultni nemocnice v Praze
Prague, Czechia, 12808
Actively Recruiting
16
Pécsi Tudományegyetem Klinikai Központ
Pécs, Baranya, Hungary, 7624
Active, Not Recruiting
17
Somogy Megyei Kaposi Mór Oktató Kórház
Kaposvár, Somogy County, Hungary, 7400
Actively Recruiting
18
Semmelweis University
Budapest, Hungary, 1088
Actively Recruiting
19
Petz Aladár Egyetemi Oktató Kórház
Győr, Hungary, 9024
Actively Recruiting
20
Tolna Varmegyei Balassa Janos Korhaz
Szekszárd, Hungary, 7100
Not Yet Recruiting
21
Komárom-Esztergom Vármegyei Szent Borbála Kórház
Tatabánya, Hungary, H-2800
Not Yet Recruiting
22
AIDPORT Sp. z o.o.
Skórzewo, Greater Poland Voivodeship, Poland, 60-185
Actively Recruiting
23
InterHem
Bialystok, Poland, 15-732
Active, Not Recruiting
24
Klinika Hematologii i Transplantologii Uniwersyteckie Centrum Kliniczne
Gdansk, Poland, 80-214
Active, Not Recruiting
25
Pratia Onkologia Katowice
Katowice, Poland, 40-519
Actively Recruiting
26
Uniwersytecki Szpital Kliniczny w Poznaniu
Poznan, Poland, 60-569
Active, Not Recruiting
27
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu
Wroclaw, Poland, 50-367
Actively Recruiting
28
Addenbrooke's Hospital
Cambridge, Cambridgeshire, United Kingdom, CB2 2QQ
Actively Recruiting
29
Derriford Hospital
Plymouth, Devon, United Kingdom, Pl6 8DH
Actively Recruiting
30
The Royal Cornwall Hospital
Truro, England, United Kingdom, TR1 3LJ
Actively Recruiting
31
Hammersmith Hospital
London, United Kingdom, W12 0HS
Actively Recruiting
Research Team
P
Pfizer CT.gov Call Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
4
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