Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
All Genders
Healthy Volunteers
NCT03059043

Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation

Led by Wenzhou Medical University · Updated on 2024-07-23

60

Participants Needed

5

Research Sites

396 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study evaluates the safety and efficacy of a viscoelastic-free method for Implantable Collamer Lens(ICL) implantation to treat high myopia. The subjects undergo randomization of ICL implantation using the viscoelastic-free method on one eye and undergoing standard method on the other one. The post-operative data are collected for analysis.

CONDITIONS

Official Title

Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation

Who Can Participate

Age: 18Years - 45Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Documented stable refraction for at least 1 year (within 0.5D)
  • Best spectacle-corrected visual acuity (BCVA) of 20/40 or better
  • Clear central cornea
  • Myopic refractive error from -0.5D to -18.0D
  • Anterior chamber depth at least 2.8 mm to endothelium
  • Endothelial cell density (ECD) more than 2000 cells/mm2
  • Pupil diameter smaller than 7.0 mm under mesopic condition
  • Discontinued hard contact lens use for 3 weeks and soft contact lens use for 1 week
Not Eligible

You will not qualify if you...

  • Preexisting ocular diseases or conditions other than myopia, or evidence of progressive or acute ocular disease
  • Evidence of connective tissue disease or other systemic diseases that may affect study results
  • Narrow angle of anterior chamber
  • Pregnant, lactating, or planning to become pregnant during the trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Guangdong General Hospital

Guangzhou, Guangdong, China, 510000

Not Yet Recruiting

2

Hunan Provincial People's Hospital

Changsha, Hunan, China, 410000

Not Yet Recruiting

3

The Eye Hispital of Wenzhou Medical University

Wenzhou, Zhejiang, China, 325000

Actively Recruiting

4

Peking Union Medical College Hospital

Beijing, China, 100000

Not Yet Recruiting

5

Shanghai Ninth People's Hospital

Shanghai, China, 200000

Not Yet Recruiting

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Research Team

A

AYong Yu, MD. PhD.

CONTACT

A

Anpeng Pan, MD.OD.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation | DecenTrialz