Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT07295275

Safety and Efficacy of Transarterial ICG Fluorescence-Guided Laparoscopic Anatomical Liver Resection

Led by West China Hospital · Updated on 2026-03-03

200

Participants Needed

3

Research Sites

130 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This multicenter, ambispective cohort study evaluates the safety and efficacy of trans-arterial Indocyanine Green (ICG) fluorescence-guided laparoscopic liver watershed resection for Hepatocellular Carcinoma (HCC). The study aims to compare the outcomes of the trans-arterial ICG staining approach versus the conventional trans-portal (portal vein) ICG staining approach.

CONDITIONS

Official Title

Safety and Efficacy of Transarterial ICG Fluorescence-Guided Laparoscopic Anatomical Liver Resection

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years
  • Postoperative histopathological diagnosis of Hepatocellular Carcinoma (HCC)
  • Underwent ICG fluorescence-guided laparoscopic anatomical liver resection
  • Child-Pugh Class A or B
  • ASA score I to III
  • ECOG Performance Status between 0 and 2
  • No invasion of major vessels (main portal vein or first-order branches, main hepatic vein)
  • No distant metastasis
Not Eligible

You will not qualify if you...

  • Pathology shows non-HCC components such as cholangiocarcinoma, combined HCC-ICC, or metastatic liver cancer
  • Presence of other active malignancies
  • Received preoperative anti-tumor therapy including TACE, ablation, radiotherapy, systemic therapy, or prior hepatectomy
  • Tumor rupture
  • Conversion to open surgery during procedure
  • Unclear surgical records regarding ICG staining method
  • Intraoperative ICG staining failure preventing fluorescence-guided resection
  • Missing data that prevents assessment of the primary study endpoint

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

Beijing Tsinghua Changgung Hospital

Beijing, Beijing Municipality, China

Actively Recruiting

2

Xuzhou Central Hospital

Xuzhou, Jiangsu, China

Actively Recruiting

3

West China Hospital

Chengdu, Sichuan, China, 610041

Actively Recruiting

Loading map...

Research Team

J

Jiwei Huang Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here