Study on the Safety and Effectiveness of Endovascular Treatment for Acute or Subacute Blood Clots in the Lower Limbs

What this Trial Is About

Researchers are studying patients with acute or subacute thromboembolic occlusions of the lower extremity, conditions where blood clots block arteries in the legs and cause limb ischemia. This observational study aims to assess the safety and clinical outcomes of endovascular treatments in real-world settings, especially for lesions classified as stage IIb or subacute, which are often excluded from clinical trials. The goal is to find optimal therapies, as current guidelines mainly recommend treatments for less severe stages. Participants receive endovascular therapy using approaches such as contralateral femoral artery, ipsilateral antegrade femoral artery, or brachial artery. If lesions are hard to pass, retrograde puncture may be used. Treatment options include mechanical thrombectomy devices, pharmacomechanical thrombectomy, percutaneous aspiration thrombectomy, catheter-directed thrombolysis, or combinations thereof, depending on lesion characteristics and hospital resources. During the study, researchers will monitor participants for up to 12 months after intervention to evaluate amputation-free survival and adverse events. Other assessments include technical success of the procedure, reintervention rates, lesion patency, quality of life changes, operation time, and medical expenses over two years. This comprehensive monitoring aims to track safety, effectiveness, and costs related to the endovascular treatments.

The Safety and Efficiency of Endovascular Treatment of Acute or Subacute Thromboembolic Occlusions of Lower Extremity.