Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
FEMALE
NCT05245812

Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy

Led by Deborah Farr, MD · Updated on 2026-03-20

90

Participants Needed

1

Research Sites

255 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single arm, single-center, prospective clinical trial designed to track the peri, post-operative and oncologic outcomes when utilizing the da-Vinci single port (SP) robotic platform to perform robotic nipple sparing mastectomy (rNSM) and immediate breast reconstruction with tissue expanders/implants and acellular dermal matrix (ADM - Alloderm), for patients with breast cancer as well as those with a high risk for breast cancer. Safety and feasibility measures will be measured as primary outcome measures. Oncological and patient satisfaction outcome measures will be measured. Our hypothesis is that SPr-NSM is equal to open NSM in terms of safety, feasibility and oncological outcomes with improved patient satisfaction as measured by nipple sensation and patient reported outcomes.

CONDITIONS

Official Title

Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy

Who Can Participate

Age: 18Years - 80Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Candidates for open nipple sparing mastectomy based on anatomic factors and tumor location, including nipple sparing resection, prophylactic mastectomy, or treatment of ductal carcinoma in-situ or clinically node negative cT1-T3 breast cancer
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent
  • Pregnant or nursing women
  • Inflammatory breast cancer
  • Skin involvement with tumor
  • Pre-operative diagnosis of Nipple Areolar Complex (NAC) tumor involvement
  • Grade 3 or higher nipple ptosis
  • Contraindicated for general anesthesia or surgery
  • Heavy current smoking history (more than 20 cigarettes per day)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UT Southwestern

Dallas, Texas, United States, 75390

Actively Recruiting

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Research Team

D

Deborah Farr, MD, FACS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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