Actively Recruiting

Age: 18Years +
All Genders
NCT05922969

Safety of Low PEEP Maneuvers During ARDS Management

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2024-07-10

50

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire, Amiens

Lead Sponsor

C

Centre Hospitalier VALENCIENNES

Collaborating Sponsor

AI-Summary

What this Trial Is About

Acute Respiratory distress syndrome (ARDS) is a severe condition in which protective ventilation is a critical point in its management. Positive end expiratory pressure (PEEP) setting can be challenging for clinicians and high PEEP has been associated with better outcome in moderate and severe ARDS. Recently, recruitment to inflation ratio and airway closure have been investigated in order to help PEEP adjustment. However, ventilatory maneuvers are performed with a low level of PEEP and therefore expose to derecruitment and oxygen desaturation. So far, the risk of oxygen desaturation has not been investigated and risk factors are unknown. The aim of this study is to evaluate the prevalence of oxygen desaturation during ventilatory maneuvers at low level of PEEP in patients with moderate or severe ARDS

CONDITIONS

Official Title

Safety of Low PEEP Maneuvers During ARDS Management

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 18 years
  • Diagnosis of ARDS
  • Receiving mechanical ventilation
  • Undergoing low PEEP maneuvers
Not Eligible

You will not qualify if you...

  • Refusal to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU Amiens

Amiens, France, 80480

Actively Recruiting

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Research Team

Y

Yoann Zerbib, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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