Actively Recruiting

Age: 18Years +
All Genders
NCT07209852

Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up

Led by Boston Scientific Corporation · Updated on 2026-05-11

140

Participants Needed

13

Research Sites

193 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational post-market clinical Follow-up study is to learn about the long-term safety, performance, and clinical benefits of pacing the left bundle branch area (LBBAP) using the INGEVITY+ pacemaker lead in patients with bradycardia who need a pacemaker.

CONDITIONS

Official Title

Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Intended for initial pacing system implant using the INGEVITY+ lead in the left bundle branch area and a Boston Scientific single- or dual-chamber pacemaker
  • Indicated for and will receive a Boston Scientific pacemaker system for symptomatic second- or third-degree AV block, bilateral bundle branch block, sinus node dysfunction, bradycardia-tachycardia syndrome, neurovascular syndromes, or chronotropic incompetence
  • Dual-chamber and atrial tracking modes indicated for patients needing AV synchrony restoration or treatment of conduction disorders
  • Willing and able to give informed consent and participate in all study visits
  • Aged 18 years or older and legally able to consent
Not Eligible

You will not qualify if you...

  • Indicated for cardiac resynchronization therapy without bradycardia indication
  • Known or suspected sensitivity to dexamethasone acetate
  • Presence of a mechanical tricuspid valve
  • Requires hemodialysis or peritoneal dialysis
  • Has had any implanted pacemaker, ICD, or CRT system before (except temporary pacing wire)
  • Currently on an active organ transplant list
  • Referred to or admitted for hospice care
  • Life expectancy less than 12 months
  • Enrolled in another concurrent study without sponsor approval
  • Pregnant or breastfeeding at enrollment
  • Unable or unwilling to comply with follow-up schedule or living too far from investigational site

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

St. Jan-Hospital

Bruges, Belgium, 8000

Actively Recruiting

2

Clinique Saint-Pierre Ottignies-Hospital

Brussels, Belgium, 1340

Actively Recruiting

3

CHRU de Lille

Lille, France, 59037

Not Yet Recruiting

4

Hospital Europeen Georges-Pompidou (HEGP)

Paris, France, 75908

Not Yet Recruiting

5

Marienhospital-Hospital

Osnabrück, Lower Saxony, Germany, 49074

Not Yet Recruiting

6

Saarland University Hospital

Homburg, Saarland, Germany, 66421

Not Yet Recruiting

7

Azienda Ospedaliero-Universitaria di Ferrara-Hospital

Ferrara, Emilia-Romagna, Italy, 44100

Not Yet Recruiting

8

Azienda Ospedaliera Ospedale Niguarda Ca Granda

Milan, Italy, 20162

Not Yet Recruiting

9

AOU Maggiore

Novara, Italy, 28100

Not Yet Recruiting

10

Virgen de las Nieves University Hospital

Granada, Spain, 18014

Actively Recruiting

11

Hospital Clinico Universitario Lozano Blesa

Zaragoza, Spain, 50009

Actively Recruiting

12

Inselspital Bern

Bern, Switzerland, 3010

Not Yet Recruiting

13

East Surrey Hospital

Redhill, Surrey, United Kingdom, RH1 5RH

Actively Recruiting

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Research Team

J

Jens Goetzke, Dipl.-Ing. (FH)

CONTACT

G

Gena Kantor, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up | DecenTrialz