Actively Recruiting

Age: 3Months - 85Years
All Genders
NCT05372263

Safety Surveillance of Targeted Drugs for Pulmonary Hypertension Using a Computerized Follow-up System: a Nationwide Cohort Study

Led by China National Center for Cardiovascular Diseases · Updated on 2025-12-04

700

Participants Needed

1

Research Sites

279 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Recruit at least 700 PH patients, follow up every 6 months based on a computerized follow-up system. Primary outcomes are adverse drug events and all-cause death.

CONDITIONS

Official Title

Safety Surveillance of Targeted Drugs for Pulmonary Hypertension Using a Computerized Follow-up System: a Nationwide Cohort Study

Who Can Participate

Age: 3Months - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age from 3 months to 85 years, no sex preference
  • Right heart catheter showing mean pulmonary artery pressure (mPAP) ≥ 25 mmHg
  • Pulmonary vascular resistance (PVR) > 3 Wood units (in children PVRi > 3 WU x m2)
  • Pulmonary artery wedge pressure (PAWP) ≤ 15 mmHg at rest
  • Diagnosed with group 1, 2, 4, or 5 pulmonary hypertension according to WHO classification
  • Taking at least one pulmonary hypertension targeted drug or calcium antagonist
  • Signed written informed consent
Not Eligible

You will not qualify if you...

  • Pulmonary hypertension related to left heart disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fuwai Hospital, Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China, 100037

Actively Recruiting

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Research Team

T

Tingting Guo, M.D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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