Actively Recruiting
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VT7208 in Healthy Participants and MS Patients
Led by Vidya Therapeutics Inc · Updated on 2025-09-03
100
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
Sponsors
V
Vidya Therapeutics Inc
Lead Sponsor
V
Vidya Therapeutics Australia Pty Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
Part 1 of this study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of VT7208 in healthy volunteers. Part 2 of this study will be an open-label, randomized study to characterize the effect of food on the pharmacokinetics of VT7208 in healthy volunteers. Part 3 of this study will evaluate the safety of VT7208 as monotherapy in patients with MS.
CONDITIONS
Official Title
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VT7208 in Healthy Participants and MS Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 65 years for Parts 1 and 2
- Age 18 to 60 years for Part 3
- Good health with no significant medical history
- Willing and able to attend all study visits and comply with study requirements, including lumbar puncture for cerebrospinal fluid collection
- Able and willing to provide written informed consent
- For Part 3, diagnosed with multiple sclerosis before Day 1 according to 2017 McDonald criteria
You will not qualify if you...
- Evidence of any clinically significant condition or disease
- Any physical or psychological condition that would prevent completing the study
- History of illicit drug use or drug abuse, harmful alcohol use, alcoholism, and/or use of smoking or nicotine products within 7 days before first dose
- History of severe allergic reactions or hypersensitivity
- Donation or loss of one or more units of whole blood or plasma within 4 weeks before dosing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CMAX
Adelaide, South Australia, Australia, 5000
Actively Recruiting
Research Team
M
MIchele DeSciscio, MBSS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
6
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