Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 65Years
All Genders
NCT07451613

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

Led by Leslie Thompson · Updated on 2026-04-13

21

Participants Needed

1

Research Sites

247 weeks

Total Duration

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Sponsors

L

Leslie Thompson

Lead Sponsor

C

California Institute for Regenerative Medicine (CIRM)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.

CONDITIONS

Official Title

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have decision-making capacity and be able to provide written informed consent.
  • Are between 18 to 65 years of age
  • Have genetically confirmed diagnosis of Huntington's Disease
  • Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture.
Not Eligible

You will not qualify if you...

  • Are pregnant
  • Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening
  • Have an implanted deep brain stimulation device.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, Irvine

Irvine, California, United States, 92697

Actively Recruiting

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Research Team

U

UCI Alpha Clinic

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

4

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