Actively Recruiting

Age: 18Years - 50Years
MALE
Healthy Volunteers
NCT06149351

Salivary Biomarkers for Concussion

Led by Sys2Diag · Updated on 2026-03-16

80

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

S

Sys2Diag

Lead Sponsor

C

Centre National de la Recherche Scientifique, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

Concussion (CC) (also called mild head trauma), which accounts for 85% of all head injuries, is very common in professional and amateur athletes. CC is an injury to the brain resulting from the direct or indirect impact of external mechanical forces, momentarily disrupting its function on a cellular level. Unlike more serious head injury (moderate and severe), which can be diagnosed using neuroimaging techniques (CT, MRI, etc.), patients suffering from CC do not necessarily show visible signs of structural abnormalities. As a result, diagnosis of CC is offen difficult. Recently, several salivary biomarkers (proteins and nucleic acids) of sport related concussion have been identified in professional athletes. However, their reference values have not been determined with sufficient robustness to enable their employment in concussion diagnostic tests.

CONDITIONS

Official Title

Salivary Biomarkers for Concussion

Who Can Participate

Age: 18Years - 50Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male participants aged between 18 and 50 years old.
  • Participants willing to comply with the study procedures.
  • Participants capable of understanding the purpose, nature, and methodology of the study.
  • Participants affiliated to a French social security system or beneficiaries of such a system.
  • Participants who have signed the non-opposition form to participate in the research.
Not Eligible

You will not qualify if you...

  • Participants not affiliated to a French social security system or not beneficiaries of such a system.
  • Participants deprived of liberty, protected adults, vulnerable individuals, or minors.
  • Participants with a proven or suspected chronic infectious disease that may introduce a risk of contamination during sample handling.
  • Participants who refuse to sign the non-opposition form to participate in the research.
  • Participants who have had a recent stroke or epilepsy event within the past two months.
  • Participants suffering from neurological diseases.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sys2Diag - Umr9005 Cnrs/Alcen

Montpellier, France, 34184

Actively Recruiting

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Research Team

W

Wendpouiré A OUEDRAOGO, Msc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Salivary Biomarkers for Concussion | DecenTrialz