Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06874868

Salivary Cortisol As a Biomarker in Patients with Temporomandibular Disorder

Led by University of Coimbra · Updated on 2025-03-13

50

Participants Needed

1

Research Sites

36 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

t is recognized that cortisol, a hormone produced by the adrenal glands, is a marker that is elevated in patients with psychological disorders, particularly anxiety. On the other hand, Temporomandibular Disorders (TMD) are a condition with a multifactorial etiology, in which emotional disturbances play a crucial role. Therefore, the aim of this study is to evaluate whether patients with TMD have higher levels of salivary cortisol compared to the general population. Initially, an assessment will be conducted using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) protocol to determine whether the patient suffer of any kind of Temporomandibular Disorder. Based on the results, individuals will be classified into two groups: the study group, consisting of patients with TMD, and the control group, composed of individuals without the disorder. Those who agree to participate will be required to sign an informed consent form. Subsequently, a saliva sample will be collected for analysis.

CONDITIONS

Official Title

Salivary Cortisol As a Biomarker in Patients with Temporomandibular Disorder

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who attend the dental clinic of the Faculty of Medicine of University of Coimbra
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Minors
  • Non-autonomous individuals

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Medicine of University of Coimbra

Coimbra, Coimbra District, Portugal, 3000-075

Actively Recruiting

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Research Team

B

Bruno Macedo, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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