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Observational Study on Salivary Cortisol Levels and Hypercortisolism in Adults with Difficult-to-Control Type 2 Diabetes
Led by Shanghai 6th People's Hospital · Updated on 2026-07-27
500
Participants Needed
1
Research Sites
26 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to explore how common hypercortisolism is among adults with type 2 diabetes that is hard to control despite standard treatments. Hypercortisolism can increase blood sugar levels and may contribute to poor diabetes control and related complications like heart disease. The study will also examine how salivary cortisol levels relate to blood sugar control in this population. Participants will be observed without receiving any new treatments. The study involves measuring salivary cortisol at different times of the day and analyzing its connection to blood sugar levels. The goal is to identify the prevalence of hypercortisolism and understand its risk factors among those with difficult-to-control type 2 diabetes. During the study, participants will provide saliva samples and have their blood sugar and other health measures evaluated. Researchers will assess the prevalence of hypercortisolism at the start and examine correlations between cortisol and glycemic levels over one week. The study includes monitoring salivary cortisol at multiple daily timepoints to gather detailed data. Participation lasts according to the schedule of assessments, with no active treatments involved.
CONDITIONS
Brief Title
Salivary Cortisol and Hypercortisolism in Type 2 Diabetes
Research Team
J
Jian Zhou
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