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ID07389148

Study of Stress Responses in Children Aged 8 to 12 With Molar Incisor Hypomineralization Compared to Healthy Children Measuring Salivary Cortisol, Heart Rate, and Oxygen Levels During Dental Exams

Led by Lokman Hekim University · Updated on 2026-02-09

90

Participants Needed

1

Research Sites

4 weeks

Total Duration

AI-Summary

What this Trial Is About

Molar incisor hypomineralization MIH is a condition affecting the enamel of permanent molars and incisors in children, often causing tooth sensitivity, discomfort, and challenges during dental care. This condition may increase dental anxiety and trigger physiological stress responses. This observational study aims to evaluate such stress responses in children with MIH by measuring salivary cortisol levels, heart rate, and oxygen saturation, then comparing these with children without MIH. The study includes two groups of children aged 8 to 12 years one group diagnosed with MIH and a healthy control group matched by age and sex. All participants will undergo a routine clinical dental examination without any treatment or intervention. Physiological stress parameters will be recorded during the visit, and saliva samples for cortisol analysis will be collected immediately after the examination using a non-invasive method. Participants will have their heart rate and oxygen saturation monitored during the dental visit, and saliva will be collected to measure cortisol levels. These assessments will help researchers understand stress responses related to dental anxiety in children with MIH. The study procedures are designed to be non-invasive and standardized. Participation lasts for the duration of the dental visit, and results may support the development of more anxiety-sensitive dental care approaches.

CONDITIONS

Brief Title

Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization

Research Team

H

Hamide Comert, DDS, PhD

M

Merve Ozdemir, DDS, PhD

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