Actively Recruiting
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours
Led by University of Erlangen-Nürnberg Medical School · Updated on 2018-06-08
96
Participants Needed
1
Research Sites
561 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected patients where salvage surgery with clear resection margins was not possible.
CONDITIONS
Official Title
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed recurrent carcinoma of the head and neck region
- Tumor stage rcT1-3
- Tumor anatomy and location suitable for brachytherapy techniques
- No or limited lymph node involvement (cN0/pN0 or rpN+ with R0 and fewer than 3 positive lymph nodes without capsule invasion)
- No distant metastasis (M0)
- Eastern Cooperative Oncology Group (ECOG) performance status 0 to 2
- Previous radiation therapy of at least 50 Gy completed more than 6 months ago
- Provided written informed consent for the study
You will not qualify if you...
- Tumor stage cT4
- More extensive lymph node involvement (rpN+ with more than 2 positive lymph nodes or capsule invasion)
- Pregnant or breastfeeding women
- Presence of collagen vascular disease
- Congenital diseases with increased radiation sensitivity, such as Ataxia telangiectasia or similar
- Psychiatric disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dept. of Radiation Therapy, University Hospital Erlangen
Erlangen, Germany, 91054
Actively Recruiting
Research Team
V
Vratislav Strnad, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here