Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT04395937

SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training

Led by University of Liege · Updated on 2026-04-14

100

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.

CONDITIONS

Official Title

SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Asthmatic patient
  • Aged 18-65 years
  • Asthma Control Questionnaire (ACQ) score greater than 1.5
  • Stable background treatment including at least one inhaled corticosteroid or an anti-leukotriene
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) greater than 35
  • Severe osteoarthritis of the knees or hips
  • Unstable angina
  • Severe uncontrolled hypertension

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chu Liege

Liège, Liege, Belgium, 4000

Actively Recruiting

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Research Team

S

Stephanie Ziant

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

3

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SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training | DecenTrialz