Actively Recruiting
Sample Collection for Ongoing Research and Product Evaluation Study
Led by Natera, Inc. · Updated on 2026-01-15
9600
Participants Needed
1
Research Sites
493 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The SCORE study is a prospective, multi-site clinical trial designed to collect blood and tissue samples, along with relevant clinical data, from participants diagnosed with various solid tumors. The collected specimens and information will be used to evaluate the clinical performance of Natera's molecular residual disease (MRD) testing across multiple cancer types. The study aims to assess the ability of Natera's assays to detect circulating tumor DNA (ctDNA) as a marker for disease recurrence and treatment response.
CONDITIONS
Official Title
Sample Collection for Ongoing Research and Product Evaluation Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Diagnosed with untreated primary solid malignancy in breast, lung, muscle invasive bladder, rectal, pancreatic, ovarian, gastroesophageal, prostate, melanoma, hepatic/liver, uterine/endometrial, or head and neck cancer
- Suspected primary malignancy of pancreatic, endometrial, bladder, or ovarian cancer based on imaging
- Eastern Cooperative Oncology Group performance status 2 or less
- Able to tolerate venipuncture for research blood draws
- Consent to provide residual tumor tissue for research
- Willing and able to comply with study requirements
- Signed informed consent obtained prior to participation
You will not qualify if you...
- Pregnant or breastfeeding
- Prior history and treatment for any cancer within the past year or having another active cancer, except surgical removal of skin squamous cell or basal cell cancers
- Initiated postoperative systemic treatment
- Undergoing or planning to undergo ctDNA testing to assess molecular residual disease, except comprehensive genomic profiling for therapy selection
- History of bone marrow or organ transplant
- Serious medical conditions that may affect ability to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Natera, Inc.
Austin, Texas, United States, 78753
Actively Recruiting
Research Team
S
SCORE Study team
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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