Actively Recruiting
SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter Study
Led by Helio Tedesco Silva Junior · Updated on 2024-11-08
500
Participants Needed
1
Research Sites
253 weeks
Total Duration
On this page
Sponsors
H
Helio Tedesco Silva Junior
Lead Sponsor
H
Hospital do Rim e Hipertensão
Collaborating Sponsor
AI-Summary
What this Trial Is About
COVID-19 is the pandemic disease caused by the SARS-CoV-2 coronavirus. It is a highly contagious viral disease, the condition of which main clinical symptoms are characterized by fever and respiratory symptoms. Evidence indicates to worse outcomes in patients with pre-existing diseases, such as diabetes, arterial hypertension, heart disease, pneumopathies, chronic kidney disease, and immunodeficiencies. Recipients of kidney transplants make prolonged use of immunosuppressive drugs to inhibit the acquired immune response, notably the activity of lymphocytes. Due to this potential to modulate the immune and inflammatory response, it is speculated that the clinical and laboratory condition of COVID-19 in these patients is atypical. Preliminary evidence suggests worse outcomes of COVID-19 in immunosuppressed patients, as carriers of cancer. However, information on kidney transplant recipients is insufficient. So far, only reports of the case are available in the literature with different clinical presentations and outcomes. The aim of this study is, therefore, to characterize the demographics, clinical and laboratory conditions, and the outcomes of COVID-19 in kidney transplant recipients in a national multicenter cohort.
CONDITIONS
Official Title
SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Kidney transplant recipients, including multi-organ recipients, at any follow-up period
- Positive COVID-19 diagnostic test by viral load, antigen, or antibody detection
- Managed as outpatient or hospitalized
- Adults and children
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital do Rim
São Paulo, Aão Paulo, Brazil, 04038-002
Actively Recruiting
Research Team
H
Helio Tedesco
CONTACT
M
Monica Nakamura
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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