Actively Recruiting

Phase Not Applicable
Age: 1Year - 18Years
FEMALE
NCT06852313

Save the Ovaries - Surgical Management of Simple Ovarian Cysts in Children and Adolescents

Led by University Children's Hospital, Zurich · Updated on 2026-04-28

80

Participants Needed

2

Research Sites

147 weeks

Total Duration

On this page

Sponsors

U

University Children's Hospital, Zurich

Lead Sponsor

U

University Children's Hospital Basel

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate which operative technique should be used for managing simple ovarian cysts in girls and adolescents. The two techniques that are being compared are laparoscopic cyst enucleation and laparoscopic cyst deroofing. The investigators will assess the effect of both techniques on the ovarian reserve and the risk of cyst recurrence.

CONDITIONS

Official Title

Save the Ovaries - Surgical Management of Simple Ovarian Cysts in Children and Adolescents

Who Can Participate

Age: 1Year - 18Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Symptomatic simple cysts 4 cm or larger with indication for surgery
  • Asymptomatic cysts 4 cm or larger requiring surgery due to persistence or growth
  • Asymptomatic cysts 4 cm or larger with other known pathology requiring surgery
  • Age between 12 months and 18 years
  • Parent/legal guardian and patient consent given; patients unable to consent must show no unwillingness
  • Symptomatic simple cysts 4 cm or larger requiring surgery on both ovaries (each ovary counted separately)
Not Eligible

You will not qualify if you...

  • Neonatal ovarian cysts (age under 12 months)
  • Age over 18 years
  • Complex cysts with solid parts or suspicion of cancer
  • Paratubal or paraovarian cysts
  • Medical conditions that prevent cyst removal (e.g., severe bleeding disorders)
  • No signed consent or insufficient language skills (German, French, or English) to consent

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Trial Site Locations

Total: 2 locations

1

University Children's Hospital Basel

Basel, Switzerland

Actively Recruiting

2

University Children's Hospital Zurich

Zurich, Switzerland

Actively Recruiting

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Research Team

U

Uchenna Kennedy, MD

CONTACT

U

Ueli Möhrlen, Prof. Dr. med.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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