Actively Recruiting

Phase 1
Age: 19Years +
All Genders
NCT05522868

SB17170 Phase 1 Clinical Trial in Solid Tumors

Led by SPARK Biopharma · Updated on 2025-11-20

50

Participants Needed

3

Research Sites

271 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Phase 1 Open-label, multicenter, dose escalation, dose expansion study

CONDITIONS

Official Title

SB17170 Phase 1 Clinical Trial in Solid Tumors

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of locally advanced or metastatic solid tumors confirmed by biopsy
  • Failure or resistance to known standard treatments with no remaining standard options
  • At least one measurable tumor lesion based on RECIST v1.1 criteria
  • ECOG Performance Status of 0 or 1
  • Expected survival of at least 3 months as assessed by the investigator
Not Eligible

You will not qualify if you...

  • Previous treatment with drugs targeting High Mobility Group Box 1 (HMGB1)
  • Chemotherapy, radiation, immunotherapy, hormone therapy, targeted therapy, biological products, or tumor embolization within 28 days before starting the study drug
  • Need to take prohibited medications or expected to take them during the study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Asan Medical Center

Seoul, South Korea

Not Yet Recruiting

2

Seoul National University Hospital

Seoul, South Korea

Not Yet Recruiting

3

Severance Hospital

Seoul, South Korea

Actively Recruiting

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Research Team

S

Sun Bin Kang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

3

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