Actively Recruiting

Phase 1
Age: 18Years - 99Years
All Genders
NCT05488522

SBRT With Atezo/Bev for HCC

Led by Abramson Cancer Center at Penn Medicine · Updated on 2026-02-20

18

Participants Needed

1

Research Sites

226 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A phase I dose escalation and pharmacodynamic study of repeated dose stereotactic body radiotherapy (SBRT) administered with concurrent atezolizumab and bevacizumab for patients with advanced hepatocellular carcinoma (HCC)

CONDITIONS

Official Title

SBRT With Atezo/Bev for HCC

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have hepatocellular carcinoma (HCC) that cannot be treated with surgery or ablation due to disease extent, other health issues, or technical reasons
  • Require systemic therapy for advanced HCC
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Abramson Cancer Center of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104-4283

Actively Recruiting

Loading map...

Research Team

E

Edgar Ben-Josef, MD

CONTACT

T

Taylor Siegal

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here