Actively Recruiting
SBRT Boost for Unfavorable Prostate Cancer'
Led by MemorialCare Health System · Updated on 2026-03-30
150
Participants Needed
3
Research Sites
887 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether giving a short course of focused radiation called an SBRT "boost" is a safe and effective way to treat prostate cancer. This boost delivers a high dose of radiation to the prostate in a non-invasive way, similar to what is done with high dose rate (HDR) brachytherapy but without using needles. The study looks at how well this treatment controls the cancer, what side effects it may cause, and how it affects patients' quality of life over time.
CONDITIONS
Official Title
SBRT Boost for Unfavorable Prostate Cancer'
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically proven prostate adenocarcinoma
- Biopsy within 12 months of registration, except for high risk patients where repeat biopsy is at physician's discretion
- Clinical Stage I-IV, MX-M0 (AJCC VERSION 9)
- M-stage determined by physical exam, CT, MRI, bone scan, PSMA PET/CT, or biopsy
- Prostate volume recommended to be 100 cc or less
- Prostate volume measurement from CT, MRI, or ultrasound within 90 days prior to registration
- Eastern Cooperative Oncology Group (ECOG) performance status 0-1
- No prior prostatectomy or cryotherapy of the prostate
- No prior radiotherapy to the prostate or lower pelvis
- No implanted hardware or material that would prevent proper treatment planning or delivery
- Completion of patient questionnaires
- Signed consent
You will not qualify if you...
- Prior prostatectomy or cryotherapy of the prostate
- Prior radiotherapy to the prostate or lower pelvis
- Implanted hardware or material that would prevent proper treatment planning or delivery according to investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Orange Coast Memorial Medical Center
Fountain Valley, California, United States, 92708
Actively Recruiting
2
Saddleback Memorial Medical Center
Laguna Hills, California, United States, 92653
Actively Recruiting
3
Long Beach Memorial Medical Center
Long Beach, California, United States, 90806
Actively Recruiting
Research Team
S
Shelbe Tolentino (Santos)
CONTACT
F
Francine Metcalf-Nodwell
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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