Actively Recruiting
Pilot Study of Mind-Body Interventions on Quality of Life, Inflammation, and Epigenetics in Lung, Colon, and Non-Hodgkin's Lymphoma Cancer Survivors
Led by Barbara Nemesure · Updated on 2025-09-23
100
Participants Needed
1
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate whether mind-body interventions, such as oncology-informed yoga and Stress Management and Resiliency Training (SMART), positively affect cancer survivors' social, emotional, and physical well-being, as well as their epigenetics. The study focuses on survivors of lung, colon, and Non-Hodgkin's lymphoma (NHL) cancers. Epigenetics refers to how environmental factors can influence gene activity without changing DNA, which this study explores alongside quality of life outcomes. Participants are randomly assigned to one of two groups: oncology-informed yoga or SMART. The yoga group attends eight weekly sessions involving light movement, breathing techniques, and meditation tailored for cancer survivors. The SMART group follows a mindfulness-based program that includes self-compassion, emotional literacy, and positive psychology principles, adapted to address stress unique to cancer survivors. Throughout the study, participants complete questionnaires assessing various aspects of quality of life, including physical, social, emotional, and functional well-being, after eight weeks. They also provide saliva samples for epigenetic analysis. Researchers monitor these measures to understand the interventions' impact on patient-reported outcomes and biological markers. The entire participation includes initial screening, intervention sessions, and follow-up assessments to track changes over time.
CONDITIONS
Brief Title
SBU-RESET: RElaxation, Stress Reduction and Epigenetics Trial in Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults over 18 years old
- Primary diagnosis of lung cancer, colon cancer, or Non-Hodgkin's lymphoma (NHL)
- At least six months since completing cancer-directed treatment (chemotherapy, targeted therapy, immunotherapy); patients with stable active disease not receiving treatment are eligible
- Able to provide a saliva sample
- Willing to provide informed consent and agree to random assignment
- Able to complete questionnaires in English
You will not qualify if you...
- Diagnosis of primary anal or primary rectal cancer
- Currently undergoing active cancer treatment
- Oral or pathological conditions preventing saliva production
- Unable to complete the full study period and follow-up
- Pregnant or planning pregnancy during the study
- Currently practicing yoga or Stress Management and Resiliency Training (SMART)
- Receiving corticosteroid therapy
- Documented fall or fainting episode within the last six months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants engage in either oncology-informed yoga or Stress Management and Resiliency Training (SMART) interventions designed to improve quality of life and reduce stress.
Weekly visits for 8 weeks
Trial Site Locations
Total: 1 location
1
Stony Brook University Cancer Center
Stony Brook, New York, United States, 11794
Actively Recruiting
Research Team
S
Stony Brook Cancer Center Clinical Trials
C
Chitra Thakur, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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