Actively Recruiting
A Registry of Spontaneous Coronary Artery Dissection: An Observational Multinational Study
Led by European Society of Cardiology · Updated on 2024-10-29
1500
Participants Needed
73
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Spontaneous coronary artery dissection (SCAD) is a recognized cause of non-atherosclerotic acute coronary syndromes, mainly affecting young women without typical risk factors. Researchers are building the first pan-European SCAD registry to improve understanding of this condition's diagnosis and management, inform guidelines, educate clinicians, and promote research. This international, multicenter, observational study includes both retrospective and prospective patient data. The study collects data without any treatment interventions, enrolling at least 500 new patients and 500 historical cases from about 30 countries and 120 sites. Patient information is gathered from their first SCAD event, at enrollment, and then yearly for up to five years or until study completion. There are no study drugs or procedures involved as it is purely observational. Participants will provide data at multiple time points including baseline and yearly follow-ups for up to five years. Researchers will review patient status, vital signs, recurrent SCAD events, imaging results, medications, menstrual and obstetric history, and discharge details. Additional information on procedures, other coronary events, symptoms, pregnancy and hormonal therapy, exercise habits, mental health, and employment after SCAD will also be collected. This allows a comprehensive understanding of SCAD over time.
CONDITIONS
Brief Title
SCAD : a Registry of Spontaneous Coronary Artery Dissection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient having signed an Informed Consent
- Patient aged 18 years and over
- SCAD clinical diagnosis within the past 10 years and available coronary angiographic imagery
You will not qualify if you...
- Patient unwilling or unable to consent
- Patients with iatrogenic or atherosclerotic coronary dissection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote) for consent and eligibility confirmation
Duration - Retrospective data collection covering the SCAD event within the past 10 years
Participants' first spontaneous coronary artery dissection (SCAD) event data are collected retrospectively from medical records.
Data collection does not require participant visits
Duration - Up to 5 years post-enrollment
Participants are followed prospectively with yearly assessments to monitor health status and recurrent SCAD events.
Annual visits for up to 5 years
Trial Site Locations
Total: 73 locations
1
ICBA - Instituto Cardiovascular de Buenos Aires
Buenos Aires, Argentina
Actively Recruiting
2
Medical University of Innsbruck, Internal Medicine III
Innsbruck, Austria
Actively Recruiting
3
Klinik Landstrasse
Vienna, Austria
Actively Recruiting
4
Klinik Ottakring
Vienna, Austria
Actively Recruiting
5
Medical University of Vienna
Vienna, Austria
Actively Recruiting
6
Landesklinikum Wiener Neustadt
Wiener Neustadt, Austria
Actively Recruiting
7
AZ Sint jan, current president of Belgian ACCA
Bruges, Belgium
Actively Recruiting
8
Cliniques Universitaires Saint-Luc (UCL)
Brussels, Belgium
Actively Recruiting
9
Universitair Ziekenhuis Brussels
Brussels, Belgium
Active, Not Recruiting
10
Antwerp University Hospital
Edegem, Belgium
Actively Recruiting
11
Ziekenhuis Oost Limburg, Interventional cardiology/Coronary Care
Genk, Belgium
Actively Recruiting
12
AZ Sint Lucas hospital
Ghent, Belgium
Active, Not Recruiting
13
Ghent University Hospital
Ghent, Belgium
Actively Recruiting
14
University Hospitals Leuven
Leuven, Belgium
Active, Not Recruiting
15
CHR La Citadelle
Liège, Belgium
Actively Recruiting
16
Les cliniques Saint Pierre
Ottignies, Belgium
Active, Not Recruiting
17
AZ Delta
Roeselare, Belgium
Actively Recruiting
18
AZ Nikolaas
Sint-Niklaas, Belgium
Actively Recruiting
19
Clinical Center University of Sarajevo
Sarajevo, Bosnia and Herzegovina
Actively Recruiting
20
Hospital Israelita Albert Einstein
São Paulo, Brazil
Actively Recruiting
21
Instituto do Coração do HCFMUSP
São Paulo, Brazil
Actively Recruiting
22
Universidade Federal de São Paulo (UNIFESP)
São Paulo, Brazil
Actively Recruiting
23
University Hospital of Split (KBC Split)
Split, Croatia
Actively Recruiting
24
Nicosia General Hospital
Nicosia, Cyprus
Actively Recruiting
25
Nemocnice Pardubického kraje
Pardubice, Czechia
Actively Recruiting
26
Hospital Na Homolce
Prague, Czechia
Actively Recruiting
27
Aarhus University Hospital
Aarhus, Denmark
Actively Recruiting
28
Rigshospitalet
Copenhagen, Denmark
Actively Recruiting
29
Herlev and Gentofte Hospital
Hellerup, Denmark
Actively Recruiting
30
Odense University Hospital
Odense, Denmark
Actively Recruiting
31
CHRU Jean Minjoz
Besançon, France
Actively Recruiting
32
Gabriel Montpied Hospital - CHU Clermont-Ferrand
Clermont-Ferrand, France
Actively Recruiting
33
Hôpital de Chartres Louis Pasteur
Le Coudray, France
Actively Recruiting
34
Cardiovascular Hospital Louis Pradel - Hospices Civils de Lyon
Lyon, France
Actively Recruiting
35
Hôpital Jacques Cartier
Massy, France
Actively Recruiting
36
Hôpital Cardiologique du Haut Lévêque - Bordeaux University
Pessac, France
Actively Recruiting
37
Schüchtermann-Klinik Bad Rothenfelde
Bad Rothenfelde, Germany
Actively Recruiting
38
Vivantes Klinikum in Friedrichshain
Berlin, Germany
Actively Recruiting
39
University Heart and Vascular Center Hamburg Eppendorf
Hamburg, Germany
Actively Recruiting
40
Robert Bosch Hospital
Stuttgart, Germany
Actively Recruiting
41
Sotiria Thoracic Diseases Hospital
Athens, Greece
Actively Recruiting
42
General Hospital of Kozani
Kozani, Greece
Actively Recruiting
43
Tehran Heart Center
Tehran, Iran
Actively Recruiting
44
Papa Giovanni XXIII Azienda Ospedaliera
Bergamo, Italy
Actively Recruiting
45
Policlinico Riuniti Foggia
Foggia, Italy
Actively Recruiting
46
Ospedale Policlinico San Martino IRCCS, Genova & Università di Genova
Genoa, Italy
Actively Recruiting
47
Presidio Ospedaliero Carlo Poma
Mantua, Italy
Actively Recruiting
48
ASST Grande Ospedale Niguarda
Milan, Italy
Actively Recruiting
49
Centro Cardiologico Monzino, IRCCS
Milan, Italy
Actively Recruiting
50
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
Milan, Italy
Actively Recruiting
51
Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy
Actively Recruiting
52
Noordwest Ziekenhuisgroep / NorthWest Clinics
Alkmaar, Netherlands
Actively Recruiting
53
Amphia Hospital
Breda, Netherlands
Actively Recruiting
54
Radboud University Medical Centre
Nijmegen, Netherlands
Actively Recruiting
55
Auckland City Hospital - Green Lane Cardiovascular Service
Auckland, New Zealand
Actively Recruiting
56
Haukeland University Hospital - Invasive cardiology
Bergen, Norway
Actively Recruiting
57
Institute of Cardiology - Department of Interventional Cardiology and Angiology
Warsaw, Poland
Actively Recruiting
58
Hospital Fernando Fonseca
Amadora, Portugal
Actively Recruiting
59
Hospital de Braga
Braga, Portugal
Actively Recruiting
60
Hospital do Espirito Santo de Evora
Evora, Portugal
Actively Recruiting
61
Centro Hospitalar Tondela Viseu
Tondela, Portugal
Actively Recruiting
62
University Hospital Centre Bezanijska Kosa
Belgrade, Serbia
Actively Recruiting
63
Cardiology Clinic, UCC Nis
Niš, Serbia
Actively Recruiting
64
National University Heart Centre Singapore
Singapore, Singapore
Actively Recruiting
65
Stredoslovensky ustav srdcovych a cievnych chorob a.s
Banská Bystrica, Slovakia
Actively Recruiting
66
Hospital Universitario de la Princesa
Madrid, Spain
Actively Recruiting
67
William Harvey Hospital
Ashford, United Kingdom
Actively Recruiting
68
Glan Clwyd Hospital
Bodelwyddan, United Kingdom
Actively Recruiting
69
Bournemouth Hospital
Bournemouth, United Kingdom
Actively Recruiting
70
Bristol Heart Institute
Bristol, United Kingdom
Actively Recruiting
71
University Hospitals
Leicester, United Kingdom
Actively Recruiting
72
Royal Brompton & Chelsea & Westminster Hospital
London, United Kingdom
Active, Not Recruiting
73
Royal Free Hospital
London, United Kingdom
Actively Recruiting
Research Team
A
Adham GHARIEB, PharmD
G
Gabrielle BONNEVILLE
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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