Actively Recruiting

Phase Not Applicable
Age: 10Years +
All Genders
Healthy Volunteers
NCT06924073

Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV

Led by University of Washington · Updated on 2025-11-14

1920

Participants Needed

25

Research Sites

171 weeks

Total Duration

On this page

Sponsors

U

University of Washington

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Ending the HIV epidemic for youth living with HIV will require implementation and optimization of evidence-based interventions that address barriers to treatment. The proposed implementation study will test a youth-led data-driven implementation strategy to scale-up an evidence-based Adolescent Transition Package (ATP) aimed at improving transition processes and post-transition clinical outcomes for youth living with HIV in Kenya. Clinics will be randomized to receive standard of care implementation through trainer of trainers or the youth-led data-driven implementation strategy alongside trainer of trainers. We will study whether the enhanced implementation strategy improves the number of youth who receive the ATP, the number of providers that initially chose to use the ATP, and the consistency with which the ATP is used over time. We will also evaluate the cost of the ATP and whether the ATP improves health outcomes among youth living with HIV, including viral suppression and retention in care. Healthcare workers at study sites will complete surveys, focus group discussions, interviews, and participate in continuous quality improvement processes. Youth will participate in surveys and focus groups, and have their routine medical records abstracted.

CONDITIONS

Official Title

Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV

Who Can Participate

Age: 10Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthcare providers must be 18 years or older
  • Healthcare providers must be employed at one of the 32 study facilities
  • Healthcare providers must provide HIV services to adolescents at their clinic
  • Adolescents and youth living with HIV aged 10 to 24 years are eligible to receive the intervention
  • Youth aged 15 to 24 years may participate in surveys and focus group discussions
  • Participants must receive HIV clinical care at one of the included clinics
  • Participants must have attended the clinic at least once after the intervention started
Not Eligible

You will not qualify if you...

  • Any individual with conditions that increase risk or prevent full participation or completion of the study

AI-Screening

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Trial Site Locations

Total: 25 locations

1

Awendo Sub County Hospital

Awendo, Kenya

Actively Recruiting

2

Uriri Sub County Hospital

Awendo, Kenya

Actively Recruiting

3

Gatundu Level 5 Hospital

Gatundu, Kenya

Actively Recruiting

4

Kiambu County Referral Hospital

Kiambu, Kenya

Actively Recruiting

5

Wangige Sub-County Hospital

Kiambu, Kenya

Actively Recruiting

6

Kikuyu (PCEA) Hospital

Kikuyu, Kenya

Actively Recruiting

7

Nazareth Hospital

Limuru, Kenya

Actively Recruiting

8

Arombe Dispensary

Migori, Kenya

Actively Recruiting

9

Dede Health Centre

Migori, Kenya

Actively Recruiting

10

Migori County Referral Hospital

Migori, Kenya

Actively Recruiting

11

St Joseph Mission Hospital (Ombo)

Migori, Kenya

Actively Recruiting

12

Baraka Dispensary (Nairobi)

Nairobi, Kenya

Actively Recruiting

13

Embakasi Health Centre

Nairobi, Kenya

Actively Recruiting

14

Kenyatta National Hospital/University of Nairobi

Nairobi, Kenya

Not Yet Recruiting

15

Mama Lucy Kibaki Hospital

Nairobi, Kenya

Actively Recruiting

16

Mbagathi District Hospital

Nairobi, Kenya

Actively Recruiting

17

Mukuru Health Centre

Nairobi, Kenya

Actively Recruiting

18

Pumwani Maternity Hospital

Nairobi, Kenya

Actively Recruiting

19

Tabitha Medical Clinic

Nairobi, Kenya

Actively Recruiting

20

Umoja Health Center

Nairobi, Kenya

Actively Recruiting

21

Rongo Sub County Hospital

Rongo, Kenya

Actively Recruiting

22

Verna Health Centre

Rongo, Kenya

Actively Recruiting

23

Ruiru Sub-County Hospital

Ruiru, Kenya

Actively Recruiting

24

Kiandutu Health Centre

Thika, Kenya

Actively Recruiting

25

Thika Level 5 Hospital

Thika, Kenya

Actively Recruiting

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Research Team

K

Kristin M Beima-Sofie, PhD, MPH

CONTACT

I

Irene Njuguna, MBChB, MPH, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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