Actively Recruiting
Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal
Led by Johns Hopkins Bloomberg School of Public Health · Updated on 2026-01-27
2070
Participants Needed
1
Research Sites
200 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins Bloomberg School of Public Health
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate whether a multifaceted community-based intervention, comprising 1) screening and lifestyle counseling by female community health volunteers (FCHVs); community health workers in Nepal, through home visits, and 2) regular Short Message Service (SMS) messages, can effectively reduce systolic blood pressure (SBP), lower fasting blood glucose, and increase smoking cessation rates among adults living in Pokhara with hypertension, type 2 diabetes, and smoking habits, respectively. The main research questions are: * Can FCHV home visits combined with regular mobile phone messages focused on blood pressure management reduce systolic blood pressure in adults with hypertension? * Can FCHV home visits combined with regular mobile phone messages focused on diabetes management lower fasting blood glucose levels in adults with type 2 diabetes? * Can FCHV home visits combined with regular mobile phone messages focused on smoking cessation increase the cessation rate among current smokers? Researchers will compare the intervention group with a usual care group, which does not receive regular FCHV home visits for managing the three aforementioned risk factors or mobile phone messages.
CONDITIONS
Official Title
Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 40 to 75 years
- Hypertension defined as blood pressure 9140/90 mmHg at two separate measurements or under treatment for hypertension
- Type 2 diabetes defined as fasting glucose 9126 mg/dL or HbA1c 96.5%, or under treatment for diabetes
- Current smoker defined as having smoked at least 100 cigarettes lifetime and currently smoking every day
- Registered on the voter list in Pokhara Metropolitan City
- Not planning to move out of Pokhara during the study period
You will not qualify if you...
- Blood pressure 9180/120 mmHg
- Blood glucose greater than 250 mg/dL or less than 54 mg/dL
- Diagnosed with secondary hypertension
- Diagnosed with diabetes other than type 2
- Having acute symptoms requiring hospitalization such as nausea, vomiting, diarrhea, abdominal pain, increased urination, excessive thirst or hunger, loss of motor or sensory function, altered mental status, chest pain or tightness, difficulty breathing, or fever
- Diagnosed as terminally ill with life expectancy of 6 months or less
- Pregnant or intending to become pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Pokhara Metropolitan City
Pokhara, Gandaki, Nepal
Actively Recruiting
Research Team
D
Dinesh Neupane, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here