Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT06544720

SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas

Led by The Affiliated Hospital of Qingdao University · Updated on 2024-08-09

18

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A multicenter, open, single arm dose escalation and dose expansion phase I study to evaluate the safety, tolerability, and efficacy of SCG142 TCR-T cells in Subjects with advanced HPV associated carcinomas.

CONDITIONS

Official Title

SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Diagnosed with HPV-associated carcinomas
  • At least one measurable lesion defined by RECIST 1.1
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Not Eligible

You will not qualify if you...

  • Active or uncontrollable infections or major medical illnesses of the heart or lungs
  • Active autoimmune diseases
  • Known active Hepatitis B or Hepatitis C infection
  • Other severe medical conditions limiting participation in the trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The affiliated hosptial of qingdao university

Qingdao, Shandong, China, 266071

Actively Recruiting

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Research Team

H

Hongying Lv

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas | DecenTrialz