Actively Recruiting

Phase Not Applicable
Age: 6Years - 90Years
All Genders
Healthy Volunteers
NCT05953233

School Inner City Air Study

Led by Massachusetts General Hospital · Updated on 2025-12-11

200

Participants Needed

1

Research Sites

306 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

B

Boston Children's Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this randomized clinical trial is to test the efficacy of high efficiency particulate air (HEPA) cleaners in reducing respiratory viral exposure and infections in elementary school classrooms. Classrooms will be randomized to active vs. sham HEPA cleaners. The main questions it aims to answer are: * Do classroom HEPA cleaners reduce exposure to viruses? * Do classroom HEPA cleaners reduce student and teacher infections? * Do classroom HEPA cleaners reduce infections in family members?

CONDITIONS

Official Title

School Inner City Air Study

Who Can Participate

Age: 6Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children in grades K-5 (age 6-12 years)
  • Attend one of the schools where the study team can collect classroom and school environmental samples
  • No plans to change schools within the next 12 months
  • Subject and/or parent or guardian can understand and provide informed consent and are willing to participate
  • Adults aged 21 or older who are parents, caretakers, household members of participating children, or teachers in participating classrooms
  • Adults able to understand and provide informed consent
Not Eligible

You will not qualify if you...

  • Children unable or contraindicated for home self-collection of nasal swab samples
  • Children with severe chronic diseases (such as cancer or genetic/congenital disorders affecting mobility)
  • Children with severe neurobehavioral, neurodevelopmental, or psychiatric disorders needing special assistance
  • Families who do not speak English or Spanish well enough to complete survey questions
  • Adults unable or contraindicated for home self-collection of nasal swab samples
  • Adults with severe chronic diseases (such as cancer or genetic/congenital disorders affecting mobility)
  • Adults with severe neurobehavioral, neurodevelopmental, or psychiatric disorders needing special assistance
  • Families who do not speak English or Spanish well enough to complete survey questions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mass General Brigham

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

P

Peggy Lai, MD MPH

CONTACT

W

Wanda Phipatanakul, MD MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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School Inner City Air Study | DecenTrialz