Actively Recruiting

Phase Not Applicable
FEMALE
NCT07489456

Screening for Dysglycemia During Postpartum Period in Women With GDM

Led by University of Sao Paulo General Hospital · Updated on 2026-05-04

182

Participants Needed

1

Research Sites

31 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood. It is associated with perinatal complications and an increased risk of developing prediabetes and type 2 diabetes after delivery. Therefore, it is recommended that a 75g oral glucose tolerance test (OGTT-75g) be performed between 6 and 12 weeks postpartum. Despite its relevance, the rate of adherence to the test is low. Recent studies also indicate that measuring blood glucose one hour after the overload may be more sensitive than the traditional two-hour measurement in the early detection of dysglycemia. This study aims to evaluate strategies for qualifying the screening of metabolic changes in the postpartum period among women with GDM. The objectives are: (1) to analyze the impact of sending reminders via WhatsApp on the attendance rate for the 75g OGTT; and (2) to compare the frequency of prediabetes and diabetes diagnoses using two different diagnostic strategies applied to the same test-the traditional (fasting and 2-hour blood glucose) and the alternative (fasting and 1-hour blood glucose).

CONDITIONS

Official Title

Screening for Dysglycemia During Postpartum Period in Women With GDM

Who Can Participate

FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of gestational diabetes mellitus according to IADPSG criteria: fasting blood glucose  92mg/dL or 75g OGTT with fasting  92mg/dL or 1-hour  180mg/dL or 2-hour  153mg/dL
  • Delivery performed at HC-FMUSP
  • Scheduling of the 75g oral glucose tolerance test between 6 and 12 weeks after delivery
  • Agreement with the informed consent form
Not Eligible

You will not qualify if you...

  • Withdrawal of consent
  • Failure to complete the OGTT due to vomiting (exclusion from analysis 2 only)

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Sao Paulo General Hospital

São Paulo, São Paulo, Brazil, 05.403-905

Actively Recruiting

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Research Team

T

Tatiana A Zaccara, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

2

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