Actively Recruiting

Age: 30Years - 69Years
All Genders
Healthy Volunteers
NCT05884983

Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma

Led by Zhongshan People's Hospital, Guangdong, China · Updated on 2025-08-15

12000

Participants Needed

1

Research Sites

204 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

All participants will be tested for EBV-related biomarkers, including EBNA1-IgA, VCA-IgA, and BNLF2b total antibody (P85-Ab), and participants with high serologic risk will be selected based on serologic test results, and dual-energy CT will be performed first for high-risk screening subjects, and dual-energy CT will be performed first for the high-risk group to record dual-energy CT examinations of those suspected of nasopharyngeal carcinoma, and then endoscopy was performed on the high-risk group to record those suspected of nasopharyngeal carcinoma under endoscopy, and finally biopsies were taken for positive lesion sites indicated by dual-energy CT and suspicious lesion sites found by endoscopy to clarify the diagnosis.

CONDITIONS

Official Title

Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma

Who Can Participate

Age: 30Years - 69Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Resident of Zhongshan City
  • No previous medical record of nasopharyngeal carcinoma
  • Able to understand, sign, and date the informed consent to participate
  • Physically well and conscious, willing to cooperate with study follow-up
Not Eligible

You will not qualify if you...

  • Presence of severe cardiovascular, liver, or kidney disease
  • Contraindications to nasopharyngeal endoscopy
  • Allergy to contrast media used in imaging

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Zhongshan People's Hospital

Zhongshan, Guangdong, China, 528403

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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