Observational Study to Predict Mental Health Risks in Adolescents Aged 11 to 17 After Mild Traumatic Brain Injury

What this Trial Is About

Researchers are investigating mental health risks in adolescents aged 11 to less than 18 years who have experienced mild traumatic brain injury mTBI. This observational, multicenter study aims to develop and validate a clinical tool that predicts which adolescents are more likely to develop new or worsening depression or anxiety after mTBI. The study also explores how racial, ethnic, social, and economic factors affect mental health care needs following mTBI. Participants diagnosed with mTBI in the emergency department will be enrolled and divided into two groups a derivation cohort and a validation cohort. Both groups will complete validated questionnaires assessing anxiety, depression, quality of life, post-concussion symptoms, and behavioral functioning. Data about the injury and medical history will also be collected. Questionnaires will be completed at the emergency visit, and again approximately 30 and 90 days later. During the study, adolescents and their parents or caregivers will complete mental health questionnaires at the emergency department visit and at one and three months afterward. Researchers will measure changes in depression and anxiety, unmet mental health care needs, quality of life, persistent symptoms, and emotional or behavioral changes. The study will continue until December 2028, with assessments focused on identifying those at risk for mental health complications after mTBI.

Screening Emotions in Adolescents at the Hospital for mTBI