Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT05049889

Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema

Led by Direction Centrale du Service de Santé des Armées · Updated on 2022-09-14

63

Participants Needed

2

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Immersion Pulmonary Edema (IPE) is a relatively new form of hemodynamic pulmonary edema. The number of cases has been increasing over the last ten years and it has become the second most common cause of hospitalization for military divers, after decompression sickness. The pathophysiological mechanisms of IPE are not completely known. Its occurrence is linked to a combination of factors related to the environmental constraints of diving, as well as to the diver's equipment. The main external factors are increased hydrostatic pressure, cold, intense effort and emotional stress. The impact of internal factors is not known. At this time, no severe forms of IPE have been identified in the military. However, it is important to identify this pathology at an early stage, even if the signs appear minor, because the continuation of underwater activity can significantly worsen the clinical picture. The risk of recurrence (greater than 15%) could result in a severe or even lethal accident.

CONDITIONS

Official Title

Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Military or civilian diver with at least 100 dives
  • Between the ages of 18 and 60
  • Good physical condition (able to run/swim for 30 minutes at a constant pace)
Not Eligible

You will not qualify if you...

  • Divers with a current temporary medical incapacity to dive
  • Persons with contraindications to physical exercise and/or scuba diving
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Equipe Résidente de Recherche Subaquatique Opérationnelle

Toulon, France, 83800

Actively Recruiting

2

Hôpital d'Instruction des Armées Sainte-Anne

Toulon, France, 83800

Actively Recruiting

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Research Team

C

CASTAGNA Olivier, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

2

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Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema | DecenTrialz