Actively Recruiting
Screening for LID Clinical Studies Unit Healthy Volunteer Protocols
Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2026-04-24
5000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: * The Laboratory of Infectious Diseases (LID) Clinical Studies Unit (CSU) enrolls healthy volunteers into clinical studies to study infectious diseases. * Viruses can be highly infectious and contagious. They cause considerable illness in the United States each year and a good example of this is influenza (the flu). The LID CSU performs clinical studies to learn about these viral infections and assist in the development of vaccines and treatments for the infections. These clinical studies include influenza "challenge studies" as well as natural history studies and phase I trials involving vaccines for viruses carried by mosquitos such as Zika or Dengue virus. * In influenza challenge studies studies, doctors expose a person to a flu virus. Then they study the flu through the body's natural healing process. This information will help to find better ways to prevent the flu and may also improve treatments for the flu. * Natural history studies and phase I trials of new vaccines are performed so the researchers can learn how some viral infections occur and if new vaccines are safe and potentially effective in preventing the infections. In some of these studies, participants experience insect bites with special clean (non-infected) insects (such as mosquitos) to better understand the role of insects in these infections. Objectives: \- To screen healthy volunteers for future CSU studies. Eligibility: \- Healthy people between the ages of 18 and 65 Design: * The 3- to 5-hour screening exam includes the following: * Medical history and physical exam * Standard blood tests including pregnancy, Hepatitis B and C, and HIV tests * Standard urine drug testing * Electrocardiogram (ECG) to test heart rhythm and function * Chest x-ray * Eligible volunteers are enrolled in the study for up to 1 year, until they take part in a CSU study or are found to be ineligible to participate. * Volunteers may withdraw from the study pool at any time.
CONDITIONS
Official Title
Screening for LID Clinical Studies Unit Healthy Volunteer Protocols
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 18 and 65 years old with no significant health problems
- Willing to consider participating in future LID Clinical Studies Unit healthy volunteer studies
- Female participants must be either not able to have children or agree to use effective contraception or abstinence as specified
- Willing to have samples stored for future research
You will not qualify if you...
- History of significant medical conditions such as chronic lung or heart disease, diabetes, kidney problems, blood disorders, immunosuppression, cancer, neurological or developmental disorders, or drug/alcohol dependency
- Any condition that the Principal Investigator believes makes participation unsafe or would prevent giving informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
R
Rani S Athota, Ph.D.
CONTACT
M
Matthew J Memoli, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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