Actively Recruiting

Age: 0Years - 100Years
All Genders
NCT05402839

Screening of Malignant Hyperthermia Susceptible Individuals

Led by Peking University Third Hospital · Updated on 2022-06-02

50

Participants Needed

1

Research Sites

988 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study intends to target patients who underwent surgery under general anesthesia during the study period and developed malignant hyperthermia during or after surgery. Therefore, the total sample size was estimated to be about 50 people based on the past incidence of this rare disease. Every year, about 20 patients and their families who developed malignant hyperthermia during or after surgery will participate in this nationwide study (estimated by the current incidence of malignant hyperthermia), and about 1-5 patients will be admitted to Peking University Third Hospital participate in this research. Relevant specimens were collected from malignant hyperthermia (MH) patients and their family members for genetic analysis to determine the mutation of MH-related pathogenic gene loci.

CONDITIONS

Official Title

Screening of Malignant Hyperthermia Susceptible Individuals

Who Can Participate

Age: 0Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing surgery under general anesthesia during the study period who developed malignant hyperthermia during or after surgery.
Not Eligible

You will not qualify if you...

  • Malignant hyperthermia was ruled out by later treatment and diagnosis.
  • The patient or family member refuses to be recruited.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191

Actively Recruiting

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Research Team

Y

Yinyin Qu, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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