Actively Recruiting
Screening Strategies Among High-risk Populations for Anal Cancer
Led by Lisa Flowers · Updated on 2025-09-08
500
Participants Needed
4
Research Sites
145 weeks
Total Duration
On this page
Sponsors
L
Lisa Flowers
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.
CONDITIONS
Official Title
Screening Strategies Among High-risk Populations for Anal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 30 and 80 years
- Individuals with chronic impaired immune status
- History of high-grade lower genital tract neoplasia
- Zubrod Performance Status of 0-2
You will not qualify if you...
- Treatment for aHSIL less than 6 months before screening
- History of anal cancer
- Pregnant women
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States, 33136
Actively Recruiting
2
University of Miami School of Medicine at Jackson Memorial Hospital (JMH)
Miami, Florida, United States, 33136
Actively Recruiting
3
Grady Memorial Hospital
Atlanta, Georgia, United States, 30303
Actively Recruiting
4
The Ponce Center
Atlanta, Georgia, United States, 30308
Actively Recruiting
Research Team
L
Lisa Flowers, MD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
4
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