Actively Recruiting
Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention
Led by University of Wisconsin, Madison · Updated on 2025-08-06
107
Participants Needed
2
Research Sites
93 weeks
Total Duration
On this page
Sponsors
U
University of Wisconsin, Madison
Lead Sponsor
W
Wisconsin Partnership Program
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary objective of the present pilot, sequential, multiple-assignment randomized trial (Pilot SMART) is to determine feasibility and acceptability of delivering (from the perspective of the treatment/intervention staff) and receiving (from the perspective of the patient) an adaptive intervention for reducing rates of opioid misuse and preventing development of opioid use disorder in individuals hospitalized for traumatic injury. A complimentary secondary objective is to ensure the feasibility of conducting a future, multi-site, full-scale SMART. Approximately 107 participants will be enrolled and can expect to be on study for up to 6 months.
CONDITIONS
Official Title
Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to speak, read, and write fluently in English
- Admitted to hospital for a traumatic injury at time of screening
- Injury severity score of 9 or greater
- Received 40 mg morphine milligram equivalent within 48 hours before screening or discharged with an opioid prescription
- Expected to be in control of own medications at discharge from hospital or short-term rehabilitation
You will not qualify if you...
- Unable to provide written consent
- Current diagnosis of cancer with life expectancy less than 12 months
- Current prescription for opioid use disorder treatment and diagnosis not in remission
- History of dementing illnesses or neurodegenerative diseases (e.g., Alzheimer's, Parkinson's, vascular dementia)
- Significant traumatic brain injury at screening
- Current spinal cord injury with persistent neurologic deficit
- Acute or emergent stroke during hospitalization
- Vision or hearing impairments preventing study participation
- Current pregnancy
- Involved in criminal justice proceedings related to illicit substance use
- Incarcerated or in police custody at enrollment
- Hospital admission with burns affecting more than 10% of body surface area
- Medical, physical, cognitive, or psychiatric conditions limiting informed consent or study completion
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
UW Health
Madison, Wisconsin, United States, 53792
Actively Recruiting
2
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
E
Ejura Salihu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
12
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