Actively Recruiting
"SCRIBBLE" Spinal Cord Injury Blood Biomarker Longitudinal Evaluation
Led by University of British Columbia · Updated on 2023-07-03
120
Participants Needed
1
Research Sites
167 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prospective, single center study designed to assess blood biomarkers for classifying injury severity and predict neurologic recovery in traumatic spinal cord injured (SCI) patients. Study will also establish the accuracy of point to care devices for SCI blood biomarkers and support the biospecimen collection for the International Spinal Cord Injury Biobank (ISCIB).
CONDITIONS
Official Title
"SCRIBBLE" Spinal Cord Injury Blood Biomarker Longitudinal Evaluation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 19 years or older
- Blunt (non-penetrating) traumatic spinal cord injury
- Baseline neurologic impairment classified as complete (AIS A) or incomplete (AIS B, C, D)
- Spinal injury involving vertebrae between C0 and L1 inclusive
- Ability to have initial blood sample drawn within 24 hours of injury
- Presence of an arterial line, central line, or intravenous line for blood collection
- Able and willing to provide informed consent
- Traumatic spinal fracture between C0 and L1 without spinal cord injury (for non-SCI spine trauma control participants)
- Initial blood sample collection within 24 hours of injury (for non-SCI spine trauma control participants)
You will not qualify if you...
- Penetrating spinal cord injury (e.g., gunshot, stab wound)
- Spinal cord injury with sensory deficit only (no motor deficit)
- Spinal injury below L1
- Isolated radiculopathy without fracture
- Isolated cauda equina injury
- Pre-existing thromboembolic disease or blood clotting disorders such as haemophilia or von Willebrand's disease
- Any other medical condition that would make study procedures dangerous or impair ability to receive treatment according to the investigator's opinion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Vancouver General Hospital
Vancouver, British Columbia, Canada, V5Z1M9
Actively Recruiting
Research Team
A
Allan Aludino
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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