Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04047992

Seated Balance Using the Indego™

Led by James J. Peters Veterans Affairs Medical Center · Updated on 2025-05-14

20

Participants Needed

1

Research Sites

412 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Exoskeleton-assisted walking (EAW) provides a new mobility option and appears to have potential therapeutic benefits for persons with SCI. However, present day technology is not sufficient to replace the wheelchair. During EAW, users stand upright, maintain static and dynamic balance by actively and passively stimulating trunk and lower limb muscles in a manner not challenged during wheelchair use. Preliminary results in our laboratory suggest that the indirect balance challenges and postural perturbations that result during EAW training transfer to better seated balance control, resulting in more independence during seated activities. The purpose of this pilot study is to determine the effects of EAW training on various measures of seated balance (primary outcomes) and body composition (secondary outcomes). Twenty people with SCI (T4 and below) who are wheelchair users for mobility and cannot walk independently will be recruited. The participants will receive 36 sessions of EAW training in 12 weeks. The outcomes will be evaluated pre (baseline) and post (24 and 36 sessions). If EAW devices can be demonstrated to help people with SCI have better seated balance, in addition to the other potential benefits that are being investigated elsewhere, then exoskeletons may have the possibility to be more readily accepted in the clinical, home environments, and by the insurance companies.

CONDITIONS

Official Title

Seated Balance Using the Indego™

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Traumatic or non-traumatic spinal cord injury with duration of at least 6 months
  • Use a wheelchair for indoor and outdoor mobility
  • Level and completeness of injury T4 and below, complete or incomplete (ISNCSCI A to D)
  • Able to hold crutches in hands with or without modifications
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Diagnosis of neurological injury other than spinal cord injury
  • Progressive condition expected to change neurological status
  • Severe medical disease or condition contraindicated by the physician
  • Incompatibility to fit with the exoskeleton device
  • Traumatic or high impact lower extremity fracture within past 2 years
  • Fragility, minimal trauma, or low impact lower extremity fracture since spinal cord injury
  • Knee bone mineral density less than 0.60 gm/cm2
  • Total hip bone mineral density T-score less than -3.5
  • Untreatable severe spasticity contraindicated by the physician
  • Flexion contracture incompatible with the device
  • Limited ankle range of motion that cannot be adapted with orthotic device (plantar flexion > 0 degrees)
  • Foot fracture confirmed by X-ray and CT
  • Untreated or uncontrolled hypertension (systolic >140 mmHg or diastolic >90 mmHg)
  • Unresolved orthostatic hypotension (systolic <90 mmHg or diastolic <60 mmHg) contraindicated by physician
  • Current pressure ulcers on arms, trunk, pelvic area, or lower extremities
  • History of seizure
  • Use of medications that lower seizure threshold
  • History of stroke, brain tumor, brain abscess, or multiple sclerosis
  • History of moderate or severe head trauma
  • History of implanted brain/spine/nerve stimulators, aneurysm clips, ferromagnetic metallic implants, or cardiac pacemaker/defibrillator
  • Psychopathology that may conflict with study objectives
  • Pregnancy or planning to become pregnant during the study period

AI-Screening

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Trial Site Locations

Total: 1 location

1

James J. Peters VA Medical Center

The Bronx, New York, United States, 10468

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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