Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT05969964

Can Second Resection for pT1 Bladder Cancer be Avoided After Initial En-Bloc Resection With Negative Safety Margins

Led by Mansoura University · Updated on 2024-10-30

370

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this \[ Can second resection for pT1 bladder carcinoma be safely avoided after initial En-Bloc Resection with negative vertical and horizontal safety margins ? is to assess the impact of avoiding re TUR on Recurrence free survival, progression free survival and cancer specific survival in patients with pT1 bladder cancer treated with ERBT and intravesical BCG through a RCT.

CONDITIONS

Official Title

Can Second Resection for pT1 Bladder Cancer be Avoided After Initial En-Bloc Resection With Negative Safety Margins

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients treated with en-bloc resection of bladder tumor and diagnosed with pT1 disease with negative vertical and horizontal safety margins on final pathology.
Not Eligible

You will not qualify if you...

  • Large tumors not suitable for en-bloc resection.
  • Residual tumor.
  • More than 4 bladder tumor lesions (multicentric tumors).
  • Presence of carcinoma in situ (CIS).
  • Positive vertical or horizontal safety margins after initial resection.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Urology and nephrology center, Mansoura University

Al Mansurah, Dakahlia Governorate, Egypt, 35516

Actively Recruiting

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Research Team

M

Mahmoud Laymon, MD,MRCS

CONTACT

A

Ahmed elassmy, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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