Actively Recruiting
Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis
Led by Ottawa Hospital Research Institute · Updated on 2025-05-30
330
Participants Needed
1
Research Sites
249 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This trial seeks to evaluate a management strategy after the acute treatment duration (≥ 3 months of therapeutic anticoagulation) for patients with cancer and catheter-related upper extremity deep vein thrombosis (DVT).
CONDITIONS
Official Title
Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older with active cancer diagnosed or treated within 6 months, or with metastatic, recurrent, progressive, or hematological malignancy not in complete remission
- Objectively confirmed catheter-related upper extremity deep vein thrombosis treated with standard therapeutic anticoagulation for at least 3 months
- Able and willing to provide informed consent
You will not qualify if you...
- Active bleeding or other contraindications to anticoagulation
- Need for ongoing therapeutic anticoagulation for other medical reasons such as atrial fibrillation or mechanical heart valve
- Anticoagulation permanently stopped or reduced to prophylactic dose before enrollment, except for brief transition to apixaban dosing as per protocol
- Known allergy, hypersensitivity, or pregnancy contraindicating apixaban use
- Use of strong inhibitors or inducers of both cytochrome P450 3A4 and P-glycoprotein
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Ottawa Hospital
Ottawa, Ontario, Canada, K1H 8L6
Actively Recruiting
Research Team
T
Tzu-Fei Wang, MD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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