Actively Recruiting

Age: 18Years +
All Genders
NCT03566797

Secondary Sclerosis Cholangitis Prospective

Led by Medical University of Graz · Updated on 2024-10-09

380

Participants Needed

1

Research Sites

488 weeks

Total Duration

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AI-Summary

What this Trial Is About

SC-CIP is increasing in patients after critical illness. Pathogenesis is still largely unclear. Gut microbiome composition, gut permeability, bacterial translocation, inflammation and/or genetic variants contribute to the pathogenesis The aim of this project is to study gut microbiome composition, gut permeability, bacterial translocation, inflammation, bile acid composition and genetic polymorphisms by conducting a prospective cohort study in patients with a high risk to develop SC-CIP.

CONDITIONS

Official Title

Secondary Sclerosis Cholangitis Prospective

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant is willing and able to give informed consent for participation in the study OR "surrogate consent" by the institutional review board.
  • Age above 18 years
  • Mechanical ventilation or extracorporeal membrane oxygenation ≥ 5 days
Not Eligible

You will not qualify if you...

  • Primary or secondary sclerosing cholangitis diagnosed before current ICU admission

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medical University Graz

Graz, Austria

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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