Actively Recruiting
Secretin in Refeeding
Led by University of California, Los Angeles · Updated on 2026-02-12
10
Participants Needed
1
Research Sites
308 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secretin--may control both urine output and how the body handles acid and base. This study will evaluate whether secretin levels are different in anorexic patients who urinate an excessive amount compared to those who urinate normal amounts. For this study, patients will have one extra blood draw before and after one meal during their hospitalization. The blood draw before the meal coincides with a standard of care blood draw. Also after the meal, subjects will be asked to provide one extra urine sample. Information from subject's medical records will also be used.
CONDITIONS
Official Title
Secretin in Refeeding
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patients aged 13 to 24 years
- Diagnosis of restrictive-type anorexia nervosa
- Hospitalized for nutritional support
- For Group 1: urine output greater than 4 cc/kg/day ("fluid dumpers")
- For Group 2: urine output less than 2 cc/kg/day ("non-dumpers")
You will not qualify if you...
- 5150 hold (psychiatric hold)
- Use of anti-depressant, anti-psychotic, or anticonvulsant medications
- Previous hospitalization within the past 6 months
- Underlying metabolic disorders unrelated to anorexia nervosa (such as chronic kidney disease, renal tubular disorders, or endocrine disorders)
- Pregnancy
- Use of NG or G-tube feeding after day 2 of hospitalization
- Receiving more than 10% of nutritional needs from supplemental feeds
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, Los Angeles (UCLA)
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
M
Misciel Macaraig
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here